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Symbol Name ID |
Tlr3
toll-like receptor 3 MGI:2156367 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Autoimmunity |
Asthma |
| Disease(s) Associated with TLR3 | ||
| asthma | ||
| type 1 diabetes mellitus |
| Mouse Phenotypes | immune system phenotype |
heart inflammation |
abnormal B cell physiology |
abnormal NK cell physiology |
abnormal NK T cell physiology |
abnormal macrophage physiology |
decreased macrophage cytokine production |
abnormal cytokine level |
abnormal interferon level |
abnormal interleukin level |
abnormal tumor necrosis factor level |
abnormal dendritic cell physiology |
abnormal cytokine secretion |
decreased interferon-beta secretion |
decreased tumor necrosis factor secretion |
decreased inflammatory response |
decreased susceptibility to Riboviria infection induced morbidity/mortality |
increased susceptibility to Picornaviridae infection induced morbidity/mortality |
increased susceptibility to Herpesvirales infection |
increased susceptibility to Coronaviridae infection |
decreased susceptibility to Riboviria infection |
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| Availability | Mouse Genotype | |||||||||||||||||||||
| Tlr3M1Btlr/Tlr3M1Btlr | ||||||||||||||||||||||
| Tlr3M2Btlr/Tlr3M2Btlr | ||||||||||||||||||||||
| Tlr3tm1Aki/Tlr3tm1Aki | * | |||||||||||||||||||||
| Tlr3tm1Flv/Tlr3tm1Flv | * | |||||||||||||||||||||
| Tlr3M1Btlr/Tlr3+ | ||||||||||||||||||||||
| Tlr3M2Btlr/Tlr3+ | ||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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